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5-MeO-DMT, or 5-methoxy-N,N-dimethyltryptamine, is a naturally occurring tryptamine compound found in various plant species and the venom of the Bufo alvarius toad. Since its first synthesis in 1936, this compound has been the subject of extensive research due to its powerful serotonergic effects and potential therapeutic applications.

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The compound’s chemical name is 5-methoxy-N,N-dimethyltryptamine, with the molecular formula C13H18N2O and a molecular weight of 218.30 g/mol. Its structure features the characteristic indole ring system of tryptamines, modified by the addition of a methoxy group at the 5-position.

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